C1.2: GENOMIC ADAPTATION IN PATHOGENIC OOMYCETES
In my current project I am focussing on the genome assemblies from high throughput sequencing reads data of some Oomycetes species, as well as the functional characterization of effectors using in silico approaches. For this I am analyzing the protein sequences of various effectors of different plant and human pathogens using computational approaches with the aim of identifying common features of these proteins for better candidate effector predictions. In particular, I am searching among the candidates for genes under positive selection as a result of host jumps and climate adaptation. We are using wealth of high throughput transcriptomics and genomics data to answer these fundamental questions. I am also interested in developing novel computational methods and pipelines to handle and analyze the data of billions of sequence reads generated from next generation sequencing techniques.
Since 2011 PhD project “Evolutionary genomics of oomycete adaptation and biotic interaction”. Supervisor Prof. Dr. Marco Thines
2009-2011 “Junior Research Fellow” Jawaharlal Nehru University, New Delhi, India.
2007-2009 “M.Sc. Bioinformatics” Guru Nanak Dev University, Punjab, India.
M.Sc. Project “Development of human protein-protein interaction database”, Jawaharlal Nehru University, New Delhi, India.
2004-2007 “B.Sc. (Hons) Bioinformatics” Panjab University, Chandigarh, India.